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Who We Are

ImmunoACT is a pioneering cell and gene therapy company, established in 2018 as a spin-off from the Biosciences & Bioengineering department at IIT Bombay. Incubated at SINE (Society for Innovation and Entrepreneurship), our journey began with a singular mission: to make life-saving gene-modified cell therapies accessible and affordable for patients battling aggressive cancers and clinically unmet disorders.

Rooted in research dating back to 2013, ImmunoACT today stands as a fully integrated cell and gene therapy company, backed by a state-of-the-art, cGMP-compliant manufacturing facility that adheres to the highest global standards. From discovery to development, clinical validation to commercialization — we control the entire value chain to ensure quality, consistency, and scalability.

Our cancer immunotherapies are designed to reprogram a patient’s own immune system to recognize and destroy cancer cells — restoring its natural ability to fight disease. These are precision-engineered, single-dose treatments intended to deliver deep, lasting responses in otherwise refractory conditions.

Developing gene-modified cell therapies is inherently complex, requiring years of R&D, rigorous clinical trials, and specialized infrastructure. Despite this, our unwavering goal remains clear: to democratize access to these breakthrough therapies by dramatically lowering their cost and expanding their reach.

Our Vision

To be the world’s leading innovator in gene & cell therapies, pioneering breakthrough treatments through scientific excellence, advanced manufacturing, and unwavering commitment to patient care.

Our Purpose & Promise

At ImmunoACT, we are committed to transforming healthcare by advancing gene and cell therapies that are not only life-changing but also accessible and affordable for every patient who can benefit—no matter how complex the science behind them.

Our Journey

  1. Developed Proprietary Lentiviral Platform & CAR-T

    2013 - 2017

    ImmunoACT laid the foundation for its advanced therapies by developing a proprietary lentiviral platform and CAR-T technology. This early R&D phase focused on building a robust genetic delivery system essential for effective T-cell engineering.

  2. Completed Process Development of high-titer vectors for ACTs

    2018

    The company completed process development of high-titer vectors for Adoptive Cell Therapies (ACTs), a critical milestone that enhanced the scalability and consistency of CAR-T cell production.

  3. Completed Preclinical Characterization and Translational R&D

    2019

    A year of translational progress, ImmunoACT completed preclinical characterization and translational R&D, paving the way for regulatory submissions and clinical-grade manufacturing.

  4. IND Submitted, Commenced Phase I Clinical Trial

    2020

    ImmunoACT submitted its IND (Investigational New Drug application) and commenced Phase I Clinical trial, marking the transition from bench research to clinical application readiness.

  5. First-in-Human Dose for Pediatric and Adult DLBCL & B-ALL at Tata Memorial Hospital

    2021

    The first significant human milestone: First-in-human doses were administered for pediatric and adult patients with DLBCL and B-ALL at Tata Memorial Hospital, a key validation step for clinical efficacy.

  6. Commencement of 1st Scaled-up GMP Manufacturing Facility & Phase II Operations

    2022

    A major operational expansion occurred with the commencement of the first scaled-up GMP manufacturing facility and initiation of Phase II operations, supporting wider clinical trial access and production capacity.

  7. Market Authorization Approval Received

    2023

    A landmark achievement: ImmunoACT received market authorization approval, confirming the therapy's safety, efficacy, and readiness for commercial use in India & Following approval, ImmunoACT completed its first commercial infusion, beginning the rollout of CAR-T therapy to real-world patients outside of trial settings.

  8. 100 Patients Dosed, 27+ Partnered Hospitals

    August, 2024

    The company reached 100 patients dosed and partnered with over 27 hospitals, indicating growing acceptance and access to the therapy across clinical networks.

  9. NexCAR19 (Talicabtagene autoleucel) Phase 1/2 clinical trial results published in The Lancet Haematology

    March, 2025

    Phase 1/2 clinical results of NexCAR19 (Taliocabtagene autoleucel) were published in The Lancet Haematology, providing global recognition of the therapy's clinical outcomes. Over 280 patients treated and 80+ hospitals partnered, demonstrating nationwide scale-up.

Our Values

Guided by innovation and driven by impact, our values shape every solution we deliver.

A

Accessible and affordable to all

Making CAR-T cell therapies accessible and cost-effective for everyone.

C

Cutting-edge research

Advancing scientific boundaries to deliver tomorrow's breakthroughs today.

T

Transforming ideas to reality

Bridging the gap between innovative concepts and real-world impact.

Our Team

Prof. Rahul Purwar, PhD

Founder
Chairman of Board

Mr. Shirish Arya

Co-Founder & Director
Corporate Strategy & Business Development

Dr. Atharva Karulkar, PhD

Co-Founder
Head-Scientific programs

Mrs. Shalini Purwar

Director
Digital & IT

Mr. Rajat Maheshwari

CFO
Finance

Dr. Sushant Kumar, PhD

Senior Scientist
R&D

Mrs. Afrin Firfiray

Principal Scientist
Quality Control

Mrs. Shreshtha Shah

Principal Scientist
Lentiviral Vector

Mr. Juber Pendhari

Scientist
Process Development

Dr. Sharvari Joshi

Manager
Quality Assurance

Pranali Patil

Senior Scientist
Plasmid

Scientific Advisory Board

Dr. Carl June, M.D

Director 

Parker Institute of Cancer Immunotherapy, University of Pennsylvania, USA. Pioneer of world's 1st CAR-T cell therapy

Dr. Avery D Posey, PhD

Assistant Professor 

Parker Institute of Cancer Immunotherapy, University of Pennsylvania, USA Expert on CAR-T for solid tumor.

Dr. Gaurav Narula, M.D

Professor

Tata Memorial Hospital, Mumbai Leading 1st CAR-T trial of paediatric B-ALL in India

Dr. Sattva Neelapu, MD

Professor

MD Anderson Cancer Center, USA. Pioneer in Clinical Studies of CAR-T Cell Therapy

Dr. Nirali Shah, M.D

Head of the Hematologic Malignancies Section

Pediatric Oncology Branch at National Cancer Institute (NCI), NIH, USA. Expert in cancer immunotherapy, including CAR-T Cell therapy for pediatric leukemia.

Business Advisory Board

Dr. Ravindranath Kancherla

Former Chairman & MD, Global Hospitals

Founded philanthropic organizations - Global University Foundation and Global Health technology life sciences university.

Dr. Satyanarayana Chava

Founder & CEO, Laurus Labs

Former COO of Matrix Laboratories, recognized with many prestigious awards including India Pharma Leader Award 2021 and BT Best CEO award (pharma) - 2022 amongst others.

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